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Studies confirmed that genetic CYP2C9 polymorphism contributed to the variability in warfarin dosage requirements in the presence of drug-disease and drug-drug interactions (24)

Levy B, Gibot S, Franck P et al (2005) Relation between muscle Na+K+ ATPase activity and raised lactate concentrations in septic shock: a prospective study

This is particularly relevant for men who consume alcohol or live in urban environments with high pollution levels

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